Traumatic Stress Disorder Today Research
Reveals low levels of cortisol which "suggests a physiological
adaptation of the hypothalamic-pituitary-adrenal axis to chronic
J Nerv Ment Dis 1990 Jun;178(6):366-
Low urinary cortisol excretion in Holocaust survivors with posttraumatic
stress disorder compared to Holocaust survivors without ptsd. Personally
I had a difficult time imagining a survivor of the Holocaust without
"...low cortisol levels may persist for decades
following exposure to trauma among individuals with chronic PTSD."
Am J Psychiatry. 1996 Jun;153(6):846.
"Increased 24-hour urinary cortisol excretion in patients with
post-traumatic stress disorder and patients with major depression, but
not in patients with fibromyalgia."
Acta Psychiatr Scand 1998 Oct;98(4):328-35
The results of our study suggest that initial cortisol levels in the
immediate aftermath of a traumatic event contribute, in part, to
subsequent symptoms of posttraumatic stress disorder.
Biol Psychiatry 2000 Nov 1;48(9):940-7
CBT: Cognitive Behavior Therapy
Open-label trial of cognitive behavior therapy for insomnia and
disturbing dreams in crime victims with PTSD. There was significantly
Am J Psychiatry 2001 Dec;158(12):2043-7
Cognitive-behavior therapy vs exposure therapy in the treatment of PTSD
in refugees. Both forms of therapy were provided and they were equally
very helpful in reducing anxiety and depression in the PTSD refugees.
Behav Res Ther 2001 Oct;39(10):1183-97
Virtual Reality Exposure Therapy for Vietnam Vets
Virtual reality exposure therapy for Vietnam veterans with posttraumatic
stress disorder. Study revealed this form of therapy is very successful
in treating Vietnam veterans.
J Clin Psychiatry 2001 Aug;62(8):617-22
Imagery Rehearsal Therapy
"Imagery rehearsal therapy for chronic nightmares in sexual assault
survivors with posttraumatic stress disorder: a randomized controlled
trial... Imagery rehearsal therapy is a brief, well-tolerated treatment
that appears to decrease chronic nightmares, improve sleep quality, and
decrease PTSD symptom severity."
JAMA. 2001 Aug 1;286(5):584-8.
Eye movement desensitization and reprocessing (EMDR): a meta-analysis.
This article reveals that EMDR was evaluated in 34
studies and it was found to be an effective treatment for non-combat
PTSD but it no more effective than other exposure techniques "and
evidence suggests that the eye movements integral to the treatment, and
to its name, are unnecessary."
J Consult Clin Psychol 2001 Apr;69(2):305-16
Efficacy and safety of paroxetine treatment for chronic PTSD: a
fixed-dose, placebo-controlled study.
"Doses of 20 and 40 mg/day of paroxetine are
effective and well tolerated in the treatment of adults with chronic
Am J Psychiatry 2001 Dec;158(12):1982-8
Efficacy of sertraline in preventing relapse of posttraumatic stress
disorder: results of a 28-week double-blind, placebo-controlled study.
The study showed that sertraline did provide protection
against relapse and provided evidence of improvement in PTSD symptoms.
Am J Psychiatry. 2001 Dec;158(12):1974-81.
Topiramate in posttraumatic stress disorder: preliminary clinical
Topiramate was tested on 3 PTSD patients and it reduced
and even eliminated "trauma-related intrusive memories and
nightmares and normalizing depressed mood" in these patients. The
study says that further study of this anti-epileptic medication for PTSD
J Clin Psychiatry 2001;62 Suppl 17:60-3
"An estimated 30% to 50% of cocaine-dependent individuals meet
criteria for lifetime PTSD."
J Subst Abuse Treat 2001 Jul;21(1):35-45
More to Come!
Last Updated: 03/30/03
[ Mental Health Today
] [ Attention
Deficit Disorder Today ] [ Bipolar
Disorder Today ] [ Borderline
Personality Disorder Today ] [ Depression
Today ] [ Gender
Identity Disorder Today ] [ Narcissistic
Personality Disorder Today ] [ Schizophrenia
Today ] [ Suicide
Intervention ] [ Mental
Health Matters ] [ Free
Health Matters for information
on a variety of mental health topics; Get
Mental Help to find
a therapist or list
your practice; and Psych
Forums for message boards on a variety of mental health topics.